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PSI-BLAST searches using hidden Markov models of structural repeats: prediction of an unusual sliding DNA clamp and of β-propellers in UV-damaged DNA-binding protein
We have designed hidden Markov models (HMMs) of structurally conserved repeats that, based on pairwise comparisons, are unconserved at the sequence level. To model secondary structure features these HMMs assign higher probabilities of transition to insert or delete states within sequence regions pre...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
2000
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC110734/ https://ncbi.nlm.nih.gov/pubmed/10982878 |
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