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DNA Sliding Clamps as Therapeutic Targets
Chromosomal DNA replication is achieved by an assembly of multi-protein complexes at the replication fork. DNA sliding clamps play an important role in this assembly and are essential for cell viability. Inhibitors of bacterial (β-clamp) and eukaryal DNA clamps, proliferating cell nuclear antigen (P...
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| Опубликовано в: : | Front Mol Biosci |
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| Главные авторы: | , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Frontiers Media S.A.
2018
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6204406/ https://ncbi.nlm.nih.gov/pubmed/30406112 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmolb.2018.00087 |
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