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Novel Gag-Pol Frameshift Site in Human Immunodeficiency Virus Type 1 Variants Resistant to Protease Inhibitors

Human immunodeficiency virus type 1 (HIV-1) variants resistant to protease inhibitors have been shown to contain a mutation in the p1/p6 Gag precursor cleavage site. At the messenger RNA level, this mutation generates a U UUU UUU sequence that is reminiscent of the U UUU UUA sequence required for ri...

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Udgivet i:J Virol
Principais autores: Doyon, Louise, Payant, Catherine, Brakier-Gingras, Léa, Lamarre, Daniel
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1998
Fag:
Animal Viruses
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC110421/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9621079/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.72.7.6146-6150.1998
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