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Maintenance of the Gag/Gag-Pol Ratio Is Important for Human Immunodeficiency Virus Type 1 RNA Dimerization and Viral Infectivity

Production of the human immunodeficiency virus type 1 (HIV-1) Gag-Pol precursor protein results from a −1 ribosomal frameshifting event. In infected cells, this generates Gag and Gag-Pol in a ratio that is estimated to be 20:1, a ratio that is conserved among retroviruses. To examine the impact of t...

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Detalhes bibliográficos
Main Authors: Shehu-Xhilaga, Miranda, Crowe, Suzanne M., Mak, Johnson
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC114093/
https://ncbi.nlm.nih.gov/pubmed/11160682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.4.1834-1841.2001
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