Maintenance of the Gag/Gag-Pol Ratio Is Important for Human Immunodeficiency Virus Type 1 RNA Dimerization and Viral Infectivity

Production of the human immunodeficiency virus type 1 (HIV-1) Gag-Pol precursor protein results from a −1 ribosomal frameshifting event. In infected cells, this generates Gag and Gag-Pol in a ratio that is estimated to be 20:1, a ratio that is conserved among retroviruses. To examine the impact of t...

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Pubblicato in:	J Virol
Autori principali:	Shehu-Xhilaga, Miranda, Crowe, Suzanne M., Mak, Johnson
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 2001
Soggetti:	Structure and Assembly
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC114093/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11160682/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.75.4.1834-1841.2001
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