Increased Misincorporation Fidelity Observed for Nucleoside Analog Resistance Mutations M184V and E89G in Human Immunodeficiency Virus Type 1 Reverse Transcriptase Does Not Correlate with the Overall Error Rate Measured In Vitro

Nucleoside analog-resistant variants of human immunodeficiency virus type 1 (HIV-1) reverse transcriptase (RT) that displayed higher in vitro polymerase fidelity were previously identified via nucleotide insertion and mispair extension assays. To evaluate the contribution of increased nucleotide ins...

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Bibliografische gegevens

Gepubliceerd in:	J Virol
Hoofdauteurs:	Drosopoulos, William C., Prasad, Vinayaka R.
Formaat:	Artigo
Taal:	Inglês
Gepubliceerd in:	American Society for Microbiology (ASM) 1998
Onderwerpen:	Animal Viruses
Online toegang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC109651/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9557711/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.72.5.4224-4230.1998
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