Increased Misincorporation Fidelity Observed for Nucleoside Analog Resistance Mutations M184V and E89G in Human Immunodeficiency Virus Type 1 Reverse Transcriptase Does Not Correlate with the Overall Error Rate Measured In Vitro

Nucleoside analog-resistant variants of human immunodeficiency virus type 1 (HIV-1) reverse transcriptase (RT) that displayed higher in vitro polymerase fidelity were previously identified via nucleotide insertion and mispair extension assays. To evaluate the contribution of increased nucleotide ins...

Descrizione completa

Dettagli Bibliografici

Pubblicato in:	J Virol
Autori principali:	Drosopoulos, William C., Prasad, Vinayaka R.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1998
Soggetti:	Animal Viruses
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC109651/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9557711/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.72.5.4224-4230.1998
Tags:	Aggiungi Tag Nessun Tag, puoi essere il primo ad aggiungerne!!