The influence of 3TC-resistance mutations E89G and M184V in the human immunodeficiency virus reverse transcriptase on mispair extension efficiency.

Two nucleoside analog resistance mutations in HIV-1 reverse transcriptase (RT), E89G and M184V, were previously shown to increase the dNTP insertion fidelity of HIV-1 RT. However, forward mutation assays using a lacZ alpha reporter gene have revealed a lack of impact on the overall error rate of the...

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Detalhes bibliográficos

Publicado no:	Nucleic Acids Res
Principais autores:	Hamburgh, M E, Drosopoulos, W C, Prasad, V R
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Oxford University Press 1998
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC147878/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9742239/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/26.19.4389
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