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Resistance to nucleoside analogs of selective mutants of human immunodeficiency virus type 2 reverse transcriptase.

We have studied selected mutants of human immunodeficiency virus type 2 (HIV-2) reverse transcriptase (RT) in a cell-free system in order to assess whether the mutant proteins exhibit a reduction in the sensitivity to nucleoside analog inhibitors similar to that of HIV-1 RT. We have modified, by sit...

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Detalhes bibliográficos
Main Authors: Perach, M, Rubinek, T, Hizi, A
Formato: Artigo
Idioma:Inglês
Publicado em: 1995
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC188600/
https://ncbi.nlm.nih.gov/pubmed/7527086
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