The Pleckstrin Homology and Phosphotyrosine Binding Domains of Insulin Receptor Substrate 1 Mediate Inhibition of Apoptosis by Insulin

Insulin and insulin-like growth factor 1 (IGF-1) evoke diverse biological effects through receptor-mediated tyrosine phosphorylation of insulin receptor substrate (IRS) proteins. We investigated the elements of IRS-1 signaling that inhibit apoptosis of interleukin 3 (IL-3)-deprived 32D myeloid proge...

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Veröffentlicht in:	Mol Cell Biol
Hauptverfasser:	Yenush, Lynne, Zanella, Christine, Uchida, Tohru, Bernal, Dolores, White, Morris F.
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Taylor & Francis 1998
Schlagworte:	Cell Growth and Development
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC109262/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9774692/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.18.11.6784
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