Loading...

Cellular effects of phosphotyrosine-binding domain inhibitors on insulin receptor signaling and trafficking.

Shc and insulin receptor substrate 1 (IRS-1) are cytoplasmic substrates of tyrosine kinase receptors that engage, localize, and activate downstream SH2 enzymes. Each contains a phosphotyrosine-binding (PTB) domain that is structurally unrelated to SH2 domains. We have designed high-affinity, cellula...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Giorgetti-Peraldi, S, Ottinger, E, Wolf, G, Ye, B, Burke, T R, Shoelson, S E
Format: Artigo
Sprog:Inglês
Udgivet: 1997
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC231843/
https://ncbi.nlm.nih.gov/pubmed/9032245
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!