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Specific and high-affinity binding of inositol phosphates to an isolated pleckstrin homology domain.

Pleckstrin homology (PH) domains are found in many signaling molecules and are thought to be involved in specific intermolecular interactions. Their binding to several proteins and to membranes containing 1-alpha-phosphatidylinositol 4,5-bisphosphate [PtdIns(4,5)P2] has been reported. A region that...

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Publicado no:Proc Natl Acad Sci U S A
Principais autores: Lemmon, M A, Ferguson, K M, O'Brien, R, Sigler, P B, Schlessinger, J
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1995
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC40633/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7479822/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.23.10472
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