Microtubules and Src homology 3 domains stimulate the dynamin GTPase via its C-terminal domain.
Dynamin is a 100-kDa GTPase that plays a critical role in the initial stages of endocytosis. Dynamin binds to microtubules, which potently stimulate its GTPase activity. Binding to Src homology 3 (SH3) domains of proteins involved in signal transduction has also recently been reported. In the presen...
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| Veröffentlicht in: | Proc Natl Acad Sci U S A |
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| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
1993
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| Schlagworte: | |
| Online-Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC48005/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7505438/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.24.11468 |
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