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Microtubules and Src homology 3 domains stimulate the dynamin GTPase via its C-terminal domain.

Dynamin is a 100-kDa GTPase that plays a critical role in the initial stages of endocytosis. Dynamin binds to microtubules, which potently stimulate its GTPase activity. Binding to Src homology 3 (SH3) domains of proteins involved in signal transduction has also recently been reported. In the presen...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Herskovits, J S, Shpetner, H S, Burgess, C C, Vallee, R B
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1993
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC48005/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7505438/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.24.11468
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