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Specific and high-affinity binding of inositol phosphates to an isolated pleckstrin homology domain.

Pleckstrin homology (PH) domains are found in many signaling molecules and are thought to be involved in specific intermolecular interactions. Their binding to several proteins and to membranes containing 1-alpha-phosphatidylinositol 4,5-bisphosphate [PtdIns(4,5)P2] has been reported. A region that...

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Détails bibliographiques
Auteurs principaux: Lemmon, M A, Ferguson, K M, O'Brien, R, Sigler, P B, Schlessinger, J
Format: Artigo
Langue:Inglês
Publié: 1995
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC40633/
https://ncbi.nlm.nih.gov/pubmed/7479822
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