Identification of pleckstrin-homology-domain-containing proteins with novel phosphoinositide-binding specificities.

The second messenger phosphatidylinositol 3,4,5-trisphosphate [PtdIns(3,4,5)P(3)] is generated by the action of phosphoinositide 3-kinase (PI 3-kinase), and regulates a plethora of cellular processes. An approach for dissecting the mechanisms by which these processes are regulated is to identify pro...

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Hauptverfasser: Dowler, S, Currie , R A, Campbell , D G, Deak, M, Kular, G, Downes, C P, Alessi, D R
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2000
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1221362/
https://ncbi.nlm.nih.gov/pubmed/11001876
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