Alkylpurine–DNA–N-Glycosylase Knockout Mice Show Increased Susceptibility to Induction of Mutations by Methyl Methanesulfonate

Alkylpurine-DNA-N-glycosylase (APNG) null mice have been generated by homologous recombination in embryonic stem cells. The null status of the animals was confirmed at the mRNA level by reverse transcription-PCR and by the inability of cell extracts of tissues from the knockout (ko) animals to relea...

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Detalhes bibliográficos

Publicado no:	Mol Cell Biol
Principais autores:	Elder, Rhoderick H., Jansen, Jacob G., Weeks, Robert J., Willington, Mark A., Deans, Bryan, Watson, Amanda J., Mynett, Kurt J., Bailey, John A., Cooper, Donald P., Rafferty, Joseph A., Heeran, Mel C., Wijnhoven, Susan W. P., van Zeeland, Albert A., Margison, Geoffrey P.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis 1998
Assuntos:	Cell Growth and Development
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC109169/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9742100/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.18.10.5828
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