Alkylpurine–DNA–N-Glycosylase Knockout Mice Show Increased Susceptibility to Induction of Mutations by Methyl Methanesulfonate

Alkylpurine-DNA-N-glycosylase (APNG) null mice have been generated by homologous recombination in embryonic stem cells. The null status of the animals was confirmed at the mRNA level by reverse transcription-PCR and by the inability of cell extracts of tissues from the knockout (ko) animals to relea...

Täydet tiedot

Bibliografiset tiedot

Julkaisussa:	Mol Cell Biol
Päätekijät:	Elder, Rhoderick H., Jansen, Jacob G., Weeks, Robert J., Willington, Mark A., Deans, Bryan, Watson, Amanda J., Mynett, Kurt J., Bailey, John A., Cooper, Donald P., Rafferty, Joseph A., Heeran, Mel C., Wijnhoven, Susan W. P., van Zeeland, Albert A., Margison, Geoffrey P.
Aineistotyyppi:	Artigo
Kieli:	Inglês
Julkaistu:	Taylor & Francis 1998
Aiheet:	Cell Growth and Development
Linkit:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC109169/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9742100/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.18.10.5828
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