Specific Mismatch Recognition in Heteroduplex Intermediates by p53 Suggests a Role in Fidelity Control of Homologous Recombination

We demonstrate that wild-type p53 inhibits homologous recombination. To analyze DNA substrate specificities in this process, we designed recombination experiments such that coinfection of simian virus 40 mutant pairs generated heteroduplexes with distinctly unpaired regions. DNA exchanges producing...

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Argitaratua izan da:	Mol Cell Biol
Egile Nagusiak:	Dudenhöffer, Christine, Rohaly, Gabor, Will, Katrin, Deppert, Wolfgang, Wiesmüller, Lisa
Formatua:	Artigo
Hizkuntza:	Inglês
Argitaratua:	Taylor & Francis 1998
Gaiak:	DNA Dynamics and Chromosome Structure
Sarrera elektronikoa:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC109118/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9710617/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.18.9.5332
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