Specific Mismatch Recognition in Heteroduplex Intermediates by p53 Suggests a Role in Fidelity Control of Homologous Recombination

We demonstrate that wild-type p53 inhibits homologous recombination. To analyze DNA substrate specificities in this process, we designed recombination experiments such that coinfection of simian virus 40 mutant pairs generated heteroduplexes with distinctly unpaired regions. DNA exchanges producing...

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Detalhes bibliográficos

Publicado no:	Mol Cell Biol
Principais autores:	Dudenhöffer, Christine, Rohaly, Gabor, Will, Katrin, Deppert, Wolfgang, Wiesmüller, Lisa
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis 1998
Assuntos:	DNA Dynamics and Chromosome Structure
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC109118/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9710617/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.18.9.5332
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