Specific Mismatch Recognition in Heteroduplex Intermediates by p53 Suggests a Role in Fidelity Control of Homologous Recombination

We demonstrate that wild-type p53 inhibits homologous recombination. To analyze DNA substrate specificities in this process, we designed recombination experiments such that coinfection of simian virus 40 mutant pairs generated heteroduplexes with distinctly unpaired regions. DNA exchanges producing...

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Dades bibliogràfiques

Publicat a:	Mol Cell Biol
Autors principals:	Dudenhöffer, Christine, Rohaly, Gabor, Will, Katrin, Deppert, Wolfgang, Wiesmüller, Lisa
Format:	Artigo
Idioma:	Inglês
Publicat:	Taylor & Francis 1998
Matèries:	DNA Dynamics and Chromosome Structure
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC109118/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9710617/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.18.9.5332
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