Specific Mismatch Recognition in Heteroduplex Intermediates by p53 Suggests a Role in Fidelity Control of Homologous Recombination

We demonstrate that wild-type p53 inhibits homologous recombination. To analyze DNA substrate specificities in this process, we designed recombination experiments such that coinfection of simian virus 40 mutant pairs generated heteroduplexes with distinctly unpaired regions. DNA exchanges producing...

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Bibliografische gegevens

Gepubliceerd in:	Mol Cell Biol
Hoofdauteurs:	Dudenhöffer, Christine, Rohaly, Gabor, Will, Katrin, Deppert, Wolfgang, Wiesmüller, Lisa
Formaat:	Artigo
Taal:	Inglês
Gepubliceerd in:	Taylor & Francis 1998
Onderwerpen:	DNA Dynamics and Chromosome Structure
Online toegang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC109118/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9710617/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.18.9.5332
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