Specific Mismatch Recognition in Heteroduplex Intermediates by p53 Suggests a Role in Fidelity Control of Homologous Recombination

We demonstrate that wild-type p53 inhibits homologous recombination. To analyze DNA substrate specificities in this process, we designed recombination experiments such that coinfection of simian virus 40 mutant pairs generated heteroduplexes with distinctly unpaired regions. DNA exchanges producing...

Полное описание

Библиографические подробности

Опубликовано в::	Mol Cell Biol
Главные авторы:	Dudenhöffer, Christine, Rohaly, Gabor, Will, Katrin, Deppert, Wolfgang, Wiesmüller, Lisa
Формат:	Artigo
Язык:	Inglês
Опубликовано:	Taylor & Francis 1998
Предметы:	DNA Dynamics and Chromosome Structure
Online-ссылка:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC109118/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9710617/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.18.9.5332
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