Base Composition of Mononucleotide Runs Affects DNA Polymerase Slippage and Removal of Frameshift Intermediates by Mismatch Repair in Saccharomyces cerevisiae

The postreplicative mismatch repair (MMR) system is important for removing mutational intermediates that are generated during DNA replication, especially those that arise as a result of DNA polymerase slippage in simple repeats. Here, we use a forward mutation assay to systematically examine the acc...

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Detalles Bibliográficos
Main Authors: Gragg, Hana, Harfe, Brian D., Jinks-Robertson, Sue
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2002
Assuntos:
DNA Dynamics and Chromosome Structure
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC139878/
https://ncbi.nlm.nih.gov/pubmed/12446792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.24.8756-8762.2002
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