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Base Composition of Mononucleotide Runs Affects DNA Polymerase Slippage and Removal of Frameshift Intermediates by Mismatch Repair in Saccharomyces cerevisiae

The postreplicative mismatch repair (MMR) system is important for removing mutational intermediates that are generated during DNA replication, especially those that arise as a result of DNA polymerase slippage in simple repeats. Here, we use a forward mutation assay to systematically examine the acc...

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Detalhes bibliográficos
Main Authors: Gragg, Hana, Harfe, Brian D., Jinks-Robertson, Sue
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC139878/
https://ncbi.nlm.nih.gov/pubmed/12446792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.24.8756-8762.2002
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