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Base Composition of Mononucleotide Runs Affects DNA Polymerase Slippage and Removal of Frameshift Intermediates by Mismatch Repair in Saccharomyces cerevisiae

The postreplicative mismatch repair (MMR) system is important for removing mutational intermediates that are generated during DNA replication, especially those that arise as a result of DNA polymerase slippage in simple repeats. Here, we use a forward mutation assay to systematically examine the acc...

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Autori principali: Gragg, Hana, Harfe, Brian D., Jinks-Robertson, Sue
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2002
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC139878/
https://ncbi.nlm.nih.gov/pubmed/12446792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.24.8756-8762.2002
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