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Base Composition of Mononucleotide Runs Affects DNA Polymerase Slippage and Removal of Frameshift Intermediates by Mismatch Repair in Saccharomyces cerevisiae

The postreplicative mismatch repair (MMR) system is important for removing mutational intermediates that are generated during DNA replication, especially those that arise as a result of DNA polymerase slippage in simple repeats. Here, we use a forward mutation assay to systematically examine the acc...

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Udgivet i:Mol Cell Biol
Principais autores: Gragg, Hana, Harfe, Brian D., Jinks-Robertson, Sue
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2002
Fag:
DNA Dynamics and Chromosome Structure
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC139878/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12446792/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.22.24.8756-8762.2002
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