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Base Composition of Mononucleotide Runs Affects DNA Polymerase Slippage and Removal of Frameshift Intermediates by Mismatch Repair in Saccharomyces cerevisiae

The postreplicative mismatch repair (MMR) system is important for removing mutational intermediates that are generated during DNA replication, especially those that arise as a result of DNA polymerase slippage in simple repeats. Here, we use a forward mutation assay to systematically examine the acc...

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Publicado en:Mol Cell Biol
Autores principales: Gragg, Hana, Harfe, Brian D., Jinks-Robertson, Sue
Formato: Artigo
Lenguaje:Inglês
Publicado: Taylor & Francis 2002
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Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC139878/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12446792/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.22.24.8756-8762.2002
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