Base Composition of Mononucleotide Runs Affects DNA Polymerase Slippage and Removal of Frameshift Intermediates by Mismatch Repair in Saccharomyces cerevisiae

The postreplicative mismatch repair (MMR) system is important for removing mutational intermediates that are generated during DNA replication, especially those that arise as a result of DNA polymerase slippage in simple repeats. Here, we use a forward mutation assay to systematically examine the acc...

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Bibliographic Details
Main Authors: Gragg, Hana, Harfe, Brian D., Jinks-Robertson, Sue
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2002
Subjects:
DNA Dynamics and Chromosome Structure
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC139878/
https://ncbi.nlm.nih.gov/pubmed/12446792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.24.8756-8762.2002
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