14-3-3 Proteins Are Required for Maintenance of Raf-1 Phosphorylation and Kinase Activity

By binding to serine-phosphorylated proteins, 14-3-3 proteins function as effectors of serine phosphorylation. The exact mechanism of their action is, however, still largely unknown. Here we demonstrate a requirement for 14-3-3 for Raf-1 kinase activity and phosphorylation. Expression of dominant ne...

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Detalhes bibliográficos

Publicado no:	Mol Cell Biol
Principais autores:	Thorson, John A., Yu, Lily W. K., Hsu, Alice L., Shih, Neng-Yao, Graves, Paul R., Tanner, J. William, Allen, Paul M., Piwnica-Worms, Helen, Shaw, Andrey S.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis 1998
Assuntos:	Cell Growth and Development
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC109108/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9710607/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.18.9.5229
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