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Cyclic AMP Blocks Cell Growth through Raf-1-Dependent and Raf-1-Independent Mechanisms

It is widely accepted that cyclic AMP (cAMP) can block cell growth by phosphorylating Raf-1 on serine 43 and inhibiting signaling to extracellular signal-regulated protein kinase. We show that the suppression of Raf-1 by cAMP is considerably more complex than previously reported. When cellular cAMP...

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Publicat a:Mol Cell Biol
Autors principals: Dumaz, Nicolas, Light, Yvonne, Marais, Richard
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 2002
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Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC133826/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11997508/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.22.11.3717-3728.2002
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