Cyclic AMP Blocks Cell Growth through Raf-1-Dependent and Raf-1-Independent Mechanisms

It is widely accepted that cyclic AMP (cAMP) can block cell growth by phosphorylating Raf-1 on serine 43 and inhibiting signaling to extracellular signal-regulated protein kinase. We show that the suppression of Raf-1 by cAMP is considerably more complex than previously reported. When cellular cAMP...

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Detalhes bibliográficos

Publicado no:	Mol Cell Biol
Principais autores:	Dumaz, Nicolas, Light, Yvonne, Marais, Richard
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis 2002
Assuntos:	Cell Growth and Development
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC133826/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11997508/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.22.11.3717-3728.2002
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