14-3-3 Proteins Are Required for Maintenance of Raf-1 Phosphorylation and Kinase Activity

By binding to serine-phosphorylated proteins, 14-3-3 proteins function as effectors of serine phosphorylation. The exact mechanism of their action is, however, still largely unknown. Here we demonstrate a requirement for 14-3-3 for Raf-1 kinase activity and phosphorylation. Expression of dominant ne...

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Main Authors: Thorson, John A., Yu, Lily W. K., Hsu, Alice L., Shih, Neng-Yao, Graves, Paul R., Tanner, J. William, Allen, Paul M., Piwnica-Worms, Helen, Shaw, Andrey S.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 1998
Fag:
Cell Growth and Development
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC109108/
https://ncbi.nlm.nih.gov/pubmed/9710607
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