Tyrosine 1101 of Tie2 Is the Major Site of Association of p85 and Is Required for Activation of Phosphatidylinositol 3-Kinase and Akt

Tie2 is an endothelium-specific receptor tyrosine kinase that is required for both normal embryonic vascular development and tumor angiogenesis and is thought to play a role in vascular maintenance. However, the signaling pathways responsible for the function of Tie2 remain unknown. In this report,...

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Hlavní autoři: Kontos, Christopher D., Stauffer, Thomas P., Yang, Wen-Pin, York, John D., Huang, Liwen, Blanar, Michael A., Meyer, Tobias, Peters, Kevin G.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 1998
Témata:
Cell Growth and Development
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC108997/
https://ncbi.nlm.nih.gov/pubmed/9632797
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