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Tyrosine 1101 of Tie2 Is the Major Site of Association of p85 and Is Required for Activation of Phosphatidylinositol 3-Kinase and Akt

Tie2 is an endothelium-specific receptor tyrosine kinase that is required for both normal embryonic vascular development and tumor angiogenesis and is thought to play a role in vascular maintenance. However, the signaling pathways responsible for the function of Tie2 remain unknown. In this report,...

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Detalhes bibliográficos
Publicado no:Mol Cell Biol
Principais autores: Kontos, Christopher D., Stauffer, Thomas P., Yang, Wen-Pin, York, John D., Huang, Liwen, Blanar, Michael A., Meyer, Tobias, Peters, Kevin G.
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC108997/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9632797/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.18.7.4131
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