Tyrosine 1101 of Tie2 Is the Major Site of Association of p85 and Is Required for Activation of Phosphatidylinositol 3-Kinase and Akt

Tie2 is an endothelium-specific receptor tyrosine kinase that is required for both normal embryonic vascular development and tumor angiogenesis and is thought to play a role in vascular maintenance. However, the signaling pathways responsible for the function of Tie2 remain unknown. In this report,...

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izdano v:	Mol Cell Biol
Principais autores:	Kontos, Christopher D., Stauffer, Thomas P., Yang, Wen-Pin, York, John D., Huang, Liwen, Blanar, Michael A., Meyer, Tobias, Peters, Kevin G.
Format:	Artigo
Jezik:	Inglês
Izdano:	Taylor & Francis 1998
Teme:	Cell Growth and Development
Online dostop:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC108997/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9632797/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.18.7.4131
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