Cargando...

The MYND Motif Is Required for Repression of Basal Transcription from the Multidrug Resistance 1 Promoter by the t(8;21) Fusion Protein

Chromosomal translocations in acute leukemia that affect the AML-1/CBFβ transcription factor complex create dominant inhibitory proteins. However, the mechanisms by which these proteins act remain obscure. Here we demonstrate that the multidrug resistance 1 (MDR-1) promoter is a target for AML/ETO t...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Lutterbach, Bart, Sun, Daxi, Schuetz, John, Hiebert, Scott W.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 1998
Materias:
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC108942/
https://ncbi.nlm.nih.gov/pubmed/9584201
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!