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Transcription, beta-like DNA polymerases and hypermutation.
This paper discusses two aspects of immunoglobulin (Ig) gene hypermutation. In the first approach, a transcription termination signal is introduced in an Ig light chain transgene acting as a mutation substrate, and transgenic lines are generated with control and mutant transgenes integrated in tande...
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| Main Authors: | , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2001
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1087696/ https://ncbi.nlm.nih.gov/pubmed/11205336 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rstb.2000.0753 |
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