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A new class of errant DNA polymerases provides candidates for somatic hypermutation.
The mechanism of somatic hypermutation of the immunoglobulin genes remains a mystery after nearly 30 years of intensive research in the field. While many clues to the process have been discovered in terms of the genetic elements required in the immunoglobulin genes, the key enzymatic players that me...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2001
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1087690/ https://ncbi.nlm.nih.gov/pubmed/11205329 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rstb.2000.0747 |
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