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Altered spectra of hypermutation in DNA repair-deficient mice.
Affinity maturation of the humoral immune response is based on the ability of immunoglobulin variable genes to undergo a process of rapid and extensive somatic mutation followed by antigenic selection for antibodies with higher affinity. While the behaviour of this somatic hypermutation phenomenon h...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2001
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1087685/ https://ncbi.nlm.nih.gov/pubmed/11205330 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rstb.2000.0742 |
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