Hypermutation of Immunoglobulin Genes in Memory B Cells of DNA Repair–deficient Mice

To investigate the possible involvement of DNA repair in the process of somatic hypermutation of rearranged immunoglobulin variable (V) region genes, we have analyzed the occurrence, frequency, distribution, and pattern of mutations in rearranged Vλ1 light chain genes from naive and memory B cells i...

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Egile Nagusiak: Jacobs, Heinz, Fukita, Yosho, van der Horst, Gijsbertus T.J., de Boer, Jan, Weeda, Geert, Essers, Jeroen, de Wind, Niels, Engelward, Bevin P., Samson, Leona, Verbeek, Sjef, de Murcia, Josiane Ménissier, de Murcia, Gilbert, e Riele, Hein t, Rajewsky, Klaus
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The Rockefeller University Press 1998
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2212309/
https://ncbi.nlm.nih.gov/pubmed/9607915
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