Inhibitory Effect of 2′-Substituted Nucleosides on Hepatitis C Virus Replication Correlates with Metabolic Properties in Replicon Cells

Nucleosides have been widely used in the treatment of viral diseases, but relatively few have been identified as inhibitors of hepatitis C virus (HCV). The modified ribonucleosides, 2′-C-methyl-adenosine and 2′-O-methyl-cytidine, are potent inhibitors of HCV replication which specifically target the...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Tomassini, Joanne E., Getty, Krista, Stahlhut, Mark W., Shim, Sung, Bhat, Balkrishen, Eldrup, Anne B., Prakash, Thazha P., Carroll, Steven S., Flores, Osvaldo, MacCoss, Malcolm, McMasters, Daniel R., Migliaccio, Giovanni, Olsen, David B.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1087620/
https://ncbi.nlm.nih.gov/pubmed/15855531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.49.5.2050-2058.2005
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados