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Keeping a good pathway down: transcriptional repression of Notch pathway target genes by CSL proteins

CSL [CBF-1, Su(H), Lag-1]-type transcription factors are the primary effectors of the Notch pathway, a signal transduction cascade that is essential for the development of all metazoan organisms. Interestingly, CSL proteins were originally classified as transcriptional repressors in vertebrates, but...

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Detalles Bibliográficos
Autor Principal: Lai, Eric C.
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2002
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1084223/
https://ncbi.nlm.nih.gov/pubmed/12223465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/embo-reports/kvf170
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