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Identification of Novel Targets of CSL-Dependent Notch Signaling in Hematopoiesis

Somatic activating mutations in the Notch1 receptor result in the overexpression of activated Notch1, which can be tumorigenic. The goal of this study is to understand the molecular mechanisms underlying the phenotypic changes caused by the overexpression of ligand independent Notch 1 by using a tet...

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Detalhes bibliográficos
Main Authors: Hamidi, Habib, Gustafason, Derek, Pellegrini, Matteo, Gasson, Judith
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3102675/
https://ncbi.nlm.nih.gov/pubmed/21637838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0020022
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