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Identification of Novel Targets of CSL-Dependent Notch Signaling in Hematopoiesis

Somatic activating mutations in the Notch1 receptor result in the overexpression of activated Notch1, which can be tumorigenic. The goal of this study is to understand the molecular mechanisms underlying the phenotypic changes caused by the overexpression of ligand independent Notch 1 by using a tet...

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Autors principals: Hamidi, Habib, Gustafason, Derek, Pellegrini, Matteo, Gasson, Judith
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3102675/
https://ncbi.nlm.nih.gov/pubmed/21637838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0020022
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