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Keeping a good pathway down: transcriptional repression of Notch pathway target genes by CSL proteins
CSL [CBF-1, Su(H), Lag-1]-type transcription factors are the primary effectors of the Notch pathway, a signal transduction cascade that is essential for the development of all metazoan organisms. Interestingly, CSL proteins were originally classified as transcriptional repressors in vertebrates, but...
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Formato: | Artigo |
Idioma: | Inglês |
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Oxford University Press
2002
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Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1084223/ https://ncbi.nlm.nih.gov/pubmed/12223465 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/embo-reports/kvf170 |
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