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Delayed, asynchronous, and reversible T-lineage specification induced by Notch/Delta signaling
Using the OP9-DL1 system to deliver temporally controlled Notch/Delta signaling, we show that pluripotent hematolymphoid progenitors undergo T-lineage specification and B-lineage inhibition in response to Notch signaling in a delayed and asynchronous way. Highly enriched progenitors from fetal liver...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Cold Spring Harbor Laboratory Press
2005
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1080135/ https://ncbi.nlm.nih.gov/pubmed/15833919 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1298305 |
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