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Maintenance of T Cell Specification and Differentiation Requires Recurrent Notch Receptor–Ligand Interactions

Notch signaling has been shown to play a pivotal role in inducing T lineage commitment. However, T cell progenitors are known to retain other lineage potential long after the first point at which Notch signaling is required. Thus, additional requirements for Notch signals and the timing of these eve...

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Detalhes bibliográficos
Main Authors: Schmitt, Thomas M., Ciofani, Maria, Petrie, Howard T., Zúñiga-Pflücker, Juan Carlos
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2211933/
https://ncbi.nlm.nih.gov/pubmed/15314075
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20040394
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