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p53 C-Terminal Phosphorylation by CHK1 and CHK2 Participates in the Regulation of DNA-Damage-induced C-Terminal Acetylation

The tumor suppressor protein p53 mediates stress-induced growth arrest or apoptosis and plays a major role in safeguarding genome integrity. In response to DNA damage, p53 can be modified at multiple sites by phosphorylation and acetylation. We report on the characterization of p53 C-terminal phosph...

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Detalhes bibliográficos
Main Authors: Ou, Yi-Hung, Chung, Pei-Han, Sun, Te-Ping, Shieh, Sheau-Yann
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1073652/
https://ncbi.nlm.nih.gov/pubmed/15659650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E04-08-0689
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