The candidate tumor suppressor BTG3 is a transcriptional target of p53 that inhibits E2F1

Proper regulation of cell cycle progression is pivotal for maintaining genome stability. In a search for DNA damage-inducible, CHK1-modulated genes, we have identified BTG3 (B-cell translocation gene 3) as a direct p53 target. The p53 transcription factor binds to a consensus sequence located in int...

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Hlavní autoři: Ou, Yi-Hung, Chung, Pei-Han, Hsu, Fu-Fei, Sun, Te-Ping, Chang, Wen-Ying, Shieh, Sheau-Yann
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2007
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1994125/
https://ncbi.nlm.nih.gov/pubmed/17690688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601825
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