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A computational study of off-target effects of RNA interference
RNA interference (RNAi) is an intracellular mechanism for post-transcriptional gene silencing that is frequently used to study gene function. RNAi is initiated by short interfering RNA (siRNA) of ∼21 nt in length, either generated from the double-stranded RNA (dsRNA) by using the enzyme Dicer or int...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1072799/ https://ncbi.nlm.nih.gov/pubmed/15800213 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gki324 |
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