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Retraction of Synapses and Dendritic Spines Induced by Off-Target Effects of RNA Interference
RNA interference (RNAi), which allows selective gene silencing, has been proposed for functional genomic analysis and for the treatment of human disease. However, induction of RNAi in mammalian cells by expression of double-stranded RNA can activate innate antiviral response pathways that perturb of...
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| Publicado no: | J Neurosci |
|---|---|
| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Society for Neuroscience
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6674211/ https://ncbi.nlm.nih.gov/pubmed/16870727 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1957-06.2006 |
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