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Retraction of Synapses and Dendritic Spines Induced by Off-Target Effects of RNA Interference
RNA interference (RNAi), which allows selective gene silencing, has been proposed for functional genomic analysis and for the treatment of human disease. However, induction of RNAi in mammalian cells by expression of double-stranded RNA can activate innate antiviral response pathways that perturb of...
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| Veröffentlicht in: | J Neurosci |
|---|---|
| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Society for Neuroscience
2006
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6674211/ https://ncbi.nlm.nih.gov/pubmed/16870727 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1957-06.2006 |
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